Arsenal will be out to avenge their opening-day defeat to Brentford when the two London rivals clash at the Emirates Stadium on Saturday, February 19.

RSD Espanyol will go head to head with Sevilla FC in a Spanish La Liga match at the RCDE Stadium on February 20.

Inter Milan will face off with US Sassuolo in an Italian Serie A match at the Stadio Giuseppe Meazza on February 20.
 

Manchester City and their English rivals Liverpool FC will take centre stage as the UEFA Champions League, Round of 16 action begins.
 

AC Milan will face off with UC Sampdoria in an Italian Serie A match at the Stadio Giuseppe Meazza on February 13.
 

Liverpool will look to haul in leaders Manchester City when they travel to Turf Moor for a Premier League clash against Burnley on Sunday, February 13.
 

Villarreal CF will battle it out with Real Madrid in a Spanish La Liga match at the Estadio de la Cerámica on February 12.
 

AC Milan will be looking to earn the bragging rights in the city for the first time since October 2020 when they face Inter Milan in the 230th Derby della Madonnina at the San Siro on Saturday, February 5.

West Ham will attempt to climb back into the Premier League's top-four when they take on struggling Watford at the London Stadium on Tuesday, Fe.bruary 8

Burkina Faso will lock horns with Senegal in a 2021 Africa Cup of Nations (AFCON) semi-final match on February 2.