Lazio will be hoping to put another dent in Inter Milan's Serie A title challenge when they do battle at the San Siro on January 9.
 

Real Betis will be looking to strengthen their grip on third place in La Liga when they face Rayo Vallecano at Vallecas on January 9.
 

Atalanta will look for a fast start in the New Year when they host Torino for a Serie A clash at the Gewiss Stadium in Bergamo on the afternoon of Thursday 6 January 2022, kick-off at 17:30.

Arsenal will host Manchester City in the opening Premier League game of 2022 at Emirates Stadium on Saturday, 01 January 2022. 
 

Getafe CF will battle with Real Madrid in a Spanish La Liga match at the Coliseum Alfonso Pérez on January 2.
 

Southampton FC will take on Tottenham Hotspur in an English Premier League match on December 28.

Arsenal will be hoping to keep the momentum going when they take on Norwich City in a Premier League clash at Carrow Road on December 26.

AC Milan will be aiming to extend their unbeaten run against Empoli to three matches when they square off in a Serie A clash at the Stadio Carlo Castellani on December 22.

Newcastle United will be eyeing a 2021/22 English Premier League upset when they host defending champions Manchester City at St James' Park on Sunday. 
 

FC Barcelona will face off with Elche CF in a Spanish La Liga match at the Camp Nou on December 18.